Maps and GPS directions to Applebee's Des Moines IA 50320 and other Applebee's Neighborhood locations in the United States. Find your nearest Applebee's Neighborhood. Applebee's Neighborhood Grill & Bar is the world's largest casual dining leader, with over 1,800 restaurants in forty-nine states and nine international countries. An attractive friendly neighborhood establishment featuring moderately priced high-quality food and beverage items table service and a comfortable atmosphere that appeals to all ages. Each Applebee's restaurant reflects its local neighborhood.
Please note: Business hours may not be accurate due to COVID-19 related restrictions. Please contact your local store to get the most updated information.